Domain and Website Information:
sabg.ae
Domain name - sabg.ae
Site title - Website Parked by AEserver.com
Go to website - Website Parked by AEserver.com
Site GEO location
Location Country - Germany
Provider - Leaseweb Deutschland GmbH
Site Logo
IP address:
Domain name servers:
ns131.aeserver.com ns130.aeserver.com
All records:
☆ sabg.ae. 3600 IN TXT "v=spf1 +mx +a +ip4:212.95.51.14 +include:relay.mailchannels.net -all"
☆ sabg.ae. 3600 IN TXT "MS=ms22304432"
☆ sabg.ae. 3600 IN MX 0 mail.sabg.ae.
☆ sabg.ae. 14400 IN A 212.95.51.14
☆ sabg.ae. 21600 IN NS ns130.aeserver.com.
☆ sabg.ae. 21600 IN NS ns131.aeserver.com.
☆ sabg.ae. 21600 IN SOA ns130.aeserver.com. noc.aeserver.com. 2024061501 3600 1800 1209600 86400
Brief facts about sabg:
Senescence-associated beta-galactosidase is a hypothetical hydrolase enzyme that catalyzes the hydrolysis of β-galactosides into monosaccharides only in senescent cells. Senescence-associated beta-galactosidase, along with p16ᴵⁿᵏ⁴ᴬ, is regarded to be a biomarker of cellular senescence. Its existence was proposed in 1995 by Dimri et al. following the observation that when beta-galactosidase assays were carried out at pH 6.0, only cells in senescence state develop staining. They proposed a cytochemical assay based on production of a blue-dyed precipitate that results from the cleavage of the chromogenic substrate X-Gal, which stains blue when cleaved by galactosidase. Since then, even more specific quantitative assays were developed for its detection at pH 6.0. Today this phenomenon is explained by the overexpression and accumulation of the endogenous lysosomal beta-galactosidase specifically in senescent cells. Its expression is not required for senescence.
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